%0 Journal Article %T Oncological safety of prophylactic breast surgery: skin-sparing and nipple-sparing versus total mastectomy %A van Verschuer, Victorien M.T. %A Maijers, Marike C. %A van Deurzen, Carolien H.M. %A Koppert, Linetta B. %J Gland Surgery %D 2015 %B 2015 %9 %! Oncological safety of prophylactic breast surgery: skin-sparing and nipple-sparing versus total mastectomy %K %X Women with a BRCA1/2 gene mutation and others with a high breast cancer risk may opt for bilateral prophylactic mastectomy. To allow for immediate breast reconstruction the skin envelope is left in situ with or without the nipple-areola complex (NAC). Although possibly leading to a more natural aesthetic outcome than the conventional total mastectomy, so-called skin-sparing mastectomies (SSM) and nipple-sparing mastectomies (NSM) may leave some breast glandular tissue in situ . The oncological risk associated with remaining breast glandular tissue is unclear. We present a case of primary breast cancer after prophylactic mastectomy followed by a review of the literature on remaining breast glandular tissue after various mastectomy techniques and oncological safety of prophylactic mastectomies. %U https://gs.amegroups.org/article/view/6029 %V 4 %N 6 %P 467-475 %@ 2227-8575