TY  - JOUR
AU  - Lee, Jin Woo
AU  - Koo, Bon Seok
PY  - 2013
TI  - The prognostic implication and potential role of  BRAF  mutation in the decision to perform elective neck dissection for thyroid cancer
JF  - Gland Surgery; Vol 2, No 4 (November 28, 2013): Gland Surgery (Neck Dissection in Differentiated Thyroid Carcinoma)
Y2  - 2013
KW  - 
N2  - The  BRAF V600E  mutation is the most common genetic change in patients with papillary thyroid cancer (PTC). Many studies have shown that detection of the  BRAF V600E  mutation is useful for confirming or establishing the preoperative diagnosis of PTC. Moreover, the mutation is associated with aggressive tumor characteristics or poor prognostic factors in most. However, whether preoperative detection of this mutation changes the treatment strategy or surgical extent, including prophylactic central neck dissection (CND), remains controversial. In this paper, we review the currently available literature regarding the potential role of the  BRAF V600E  mutation in the decision to perform elective neck dissection for PTC.
UR  - https://gs.amegroups.org/article/view/2972