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Does multiparametric US improve diagnostic accuracy in the characterization of small testicular masses?

  
@article{GS25117,
	author = {Alfonso Reginelli and Alfredo D’Andrea and Alfredo Clemente and Andrea Izzo and Fabrizio Urraro and Fernando Scala and Valerio Nardone and Cesare Guida and Michele Scialpi and Salvatore Cappabianca},
	title = {Does multiparametric US improve diagnostic accuracy in the characterization of small testicular masses?},
	journal = {Gland Surgery},
	volume = {0},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Background: Recent advances in ultrasonography (US) have produced new innovative techniques for the non-invasive assessment of testicular masses. The aim of this study was to investigate the diagnostic performance of multiparametric US, including gray-scale, Color-power Doppler and real-time elastography (RTE) analysis, in the characterization of testicular lesions. 
Methods: Fifty-four patients (median 42.2 years; range, 10–64 years) with testicular lesions detected with gray-scale US and power Doppler US were evaluated with RTE. The tissue elasticity was assessed in all lesions. Hard lesions were suspected of being malignant while testicular lesions with normal or decreased tissue stiffness (soft lesions) were considered benign. Intraoperative findings were the standard of reference. Sensitivity, specificity, negative predictive value, positive predictive value, and diagnostic accuracy were calculated for each US method and in combination.
Results: Forty-six of the 54 lesions (85.2%) were testicular malignant tumors. Thirty-five out of 46 (76%) were ≥2 cm [seminomas (n=18), mixed seminomatous and/or nonseminomatous tumors (n=9), embryonal carcinomas (n=2), immature teratomas (n=3) and Leydig cell tumors (n=3)] while the remaining 11 tumors were },
	url = {http://gs.amegroups.com/article/view/25117}
}