Metastases free thyroid cancer patients harbouring TERT mutations may benefit from a more intensive treatment and follow-up

Alessandro Antonelli, Silvia Martina Ferrari, Giusy Elia, Armando Patrizio, Poupak Fallahi


The telomerase reverse transcriptase (TERT) was discovered in the beginning of 1980s. This enzyme is able to preserve the chromosomes integrity by adding to their ends a specific nucleotide sequences called “telomeres” (1,2).