Natural history of metaplastic squamous cell breast cancer: a case report and literature review on surgical management

Geok-Hoon Lim, Hannah Angela Acosta, Mihir Ananta Gudi


Metaplastic squamous cell breast cancer is an extremely rare subtype, accounting for less than 1% of all invasive breast cancers. As a result, there is sparse data in literature relating to its presentation and management. We report the first known case of metaplastic squamous cell breast cancer which was detected on screening mammogram and followed up as the patient delayed her treatment. This case highlights the aggressive natural behaviour of this subtype and importance of early treatment. The surgical management of this rare entity was reviewed.